Skip to Content
Knowledge Bank

Glossary of terms

  • Abnormalities

    A condition that differs from the normal physical or mental state.

    Top of panel Close
  • Achilles tendon

    Is the tendon that joinis the calf muscles to the bone in the heel.
    It is the thickest and strongest tendon in the body. In an adult the achilles tendon it is approximately 15cm long.

    Top of panel Close
  • Acute

    A disease with a rapid onset and/or a short course as opposed to Chronic which is a persistent and lasting disease or medical condition or one that has developed slowly

    Top of panel Close
  • Acute phase protein

    is a protein produced in the liver which increases during inflammation, e.g., C reactive protein

    Top of panel Close
  • Acupuncture

    is the insertion of very fine needles into the skin at particular points on the body, to prevent or treat ill health or maintain good health.
    This procedure is thought to stimulate the body’s ability to heal.

    Top of panel Close
  • Adherence

    is when a patient follows their advised treatment programme

    Top of panel Close
  • Adolescent

    A youth in their teenage years

    Top of panel Close
  • Adolescence

    The period in development between the onset of puberty and adulthood. It usually begins between 11 and 13 years of age with the appearance of secondary sex characteristics and spans the teen years terminating at 18 to 20 years of age with the completion of the development of adulthood.

    Top of panel Close
  • Aetiology

    Is the part of medical science dealing with causes of disease

    Top of panel Close
  • Albumin

    is a blood protein which falls in severe inflammation, malnutrition and some kinds of kidney disease.

    Top of panel Close
  • Alexander technique

    can be used to help you to identify and prevent the harmful postural habits that aggravate, or may be the cause of, stress and or pain.

    Top of panel Close
  • Alkaline phosphatase

    liver enzyme monitored in patients who are taking methotrexate or azathioprine

    Top of panel Close
  • Allergies and allergic reactions

    are an over reaction by the immune system to certain substances. In non allergic people these substances are seen as harmless but in allergic people the substance is mistakenly identified as foreign and part of the immune system is turned on which in turn causes symptoms rather than protection. The most common site for allergic reactions is the skin. Uncomplicated reactions can be treated with an antihistamine drug which blocks the effects of histamine on the skin.

    Top of panel Close
  • Anabolic steroids

    are drugs that resemble male hormones such as testosterone . Athletes sometimes take them to try and increase their weight, strength, speed and endurance.

    Top of panel Close
  • Anaemia

    is when there is a decrease of haemoglobin in the blood to levels below the normal range. Anaemia may be caused by a decrease in red cell production, an increase in red cell destruction, or a loss of blood.

    Top of panel Close
  • Analysis tools

    There are number of ways psoriasis and psoriatic arthritis are assessed by doctors and healthcare providers, these include:

    • The psoriasis area and severity index (PASI)
    • The dermatology life quality index (DLQI)
    • The disability index of health assessment questionnaire (HAQ)
    • The nail psoriasis severity index (NAPSI)
    • The short form 36 health survey (SF-36)

    The use of these and other assessment tools help guide treatment decisions and can show whether a treatment is working (showing benefit).

    Top of panel Close
  • Anti-malarial

    drug called chloroquine is a known aggravator of psoriasis. Consult your doctor or healthcare provider before travelling.

    Top of panel Close
  • Antibody

    an antibody is a protein produced by immune system cells that binds to antigens on foreign particles/bodies allowing other elements of the immune system to attack, destroy or remove them

    Top of panel Close
  • Anticoagulant

    is a substance that prevents or delays coagulation of the blood.

    Top of panel Close
  • Antigens

    are the fingerprints detected by the immune system that are found on every potentially harmful organism that enters the body.

    Top of panel Close
  • Antinuclear Antibody test (ANA)

    is a sensitive screening test used to detect autoimmune diseases. Antinuclear Antibody (ANAs) are found in people whose immune system may be predisposed to cause inflammation against their own body tissues.

    Top of panel Close
  • Antipruritic

    pertaining to a substance or procedure that tends to relieve or prevent itching.

    Top of panel Close
  • Aromatherapy

    is the use of plant oils for preventative care, healing and general well-being. Essential oils can be used in different ways, including massage, bathing and inhalation. When essential oils are inhaled, the part of the brain that is connected to smell is stimulated and the impulse is transmitted to the emotional centre of the brain.

    Top of panel Close
  • Arthralgia

    is a pain in a joint

    Top of panel Close
  • Arthropathy

    (pronounced as ar throp ath e) - Any disease affecting a joint such as arthritis

    Top of panel Close
  • Arthroscopy

    is a surgical procedure used to inspect and treat problems inside a joint, allowing a surgeon to look inside a joint to determine what is wrong. The procedure is carried out using an arthroscope, which is a narrow tube with a light source attached to a small video camera, this enters via a small incision in the skin (keyhole) and then transmits pictures back to a TV monitor.

    Top of panel Close
  • Aspiration

    is to take or aspirate a joint by taking fluid out of a joint with a needle attached to a syringe.

    Top of panel Close
  • AST

    is a liver enzyme - see alkaline phosphatase

    Top of panel Close
  • Ayurveda

    is the traditional medicine of India.It emphasises creating balance in the body through diet, lifestyle, exercise, and body cleansing, and on the health of the mind, body, and spirit.

    Top of panel Close
  • Ayurvedic medicine

    is a complementary therapy system which involves detoxification, diet, exercise, the use of herbs and other techniques to improve mental and emotional health.

    Top of panel Close
  • Bacteria

    are small cells that can cause diseases such as sore throats, tonsillitis, ear infections, etc although not all bacteria are bad. Good bacterial live in the intestines and help to use the nutrients in the food we eat and help to make waste from what is left over.

    Top of panel Close
  • British Association of Dermatologists (BAD)

    is the professional organisation for Trainee, Consultant and Non-Consultant Career Grade (NCCG) dermatologists in the UK and Eire. Established in 1920, it is a registered charity with an incorporated body of trustees, the Executive Committee, who are all dermatologists elected by the membership. The Officers, supported by the professional staff carry out the day to day business from Willan House, the headquarters building in central London

    Top of panel Close
  • Baker's cyst

    A swelling behind the knee which contains fluid, common in osteoarthritis and rheumatoid arthritis, and sometimes psoriatic arthritis.

    Top of panel Close
  • Biological therapy

    drugs made from natural proteins using biotechnology

    Top of panel Close
  • Biotechnology

    is the use of recombinant DNA, cell fusion, and new bioprocessing techniques applied to research and product development.

    Top of panel Close
  • Birthmarks (Naevus)

    are darker and sometimes coloured patches on the skin that are either present at birth, or develop very soon afterwards the most common of which is known as the “strawberry” birthmark. Most birthmarks are harmless and don't need any treatment. However, occasionally there are medical reasons that mean it's necessary for the birthmark to be treated. You may also wish to have treatment for cosmetic reasons.

    Top of panel Close
  • Blackheads

    are caused by dried plugs of fatty material in the ducts of the sebaceous (oil secreting) glands of the skin causing a black colour at the surface of the plugs. Blackheads should never be squeezed as this increases the risk of infection.

    Top of panel Close
  • Blepharitis

    is a crusty scaling of the eyelid which can be fairly common in children.

    Top of panel Close
  • Blisters

    are the outpouring of fluid under the outer layer of the skin as a result of local damage. They can often be caused by friction on tender skin (on the hands from unusual physical work or on the feet by ill fitting shoes) by heat (as in burns and scalds) and also by irritating chemicals. Blisters should be kept clean to avoid infection.

    Top of panel Close
  • Boils

    are painful red swellings in the skin caused by a bacterial infection of a hair follicle or sweat gland. They are contagious via the pus (bacterial) and therefore if left untreated could develop into further boils or in extreme cases to blood poisoning.

    Top of panel Close
  • Bowen therapy

    involves a series of detailed gentle moves combined with rest periods, which are performed over a period of up to one hour. The goal is to cause a reset of the body systems and reinvigorate the body’s self-healing processes.

    Top of panel Close
  • British Society for Rheumatology (BSR)

    head office is based in London is a registered charity. Its principal activity is to advance knowledge of arthritis and other muscoloskeletal conditions

    Top of panel Close
  • Burns

    Damage caused to the skin by either dry or wet heat. The severity of burns is assessed by the amount of skin that is damaged.

    • First degree burns cause reddening of the skin and affect the top layer of the skin only
    • Second degree burns cause the formation of blisters
    • Third degree burns destroy the full skin thickness leaving the area looking white or charred.
    Top of panel Close
  • Bursa

    is a fibrous sac between certain tendons and the bones beneath them

    Top of panel Close
  • C-Reactive Protein (CRP)

    is a protein produced in the liver which rises in quantity in the blood when there is active Inflammation. In psoriatic arthritis pain may be present with some swelling in a number of small joints without this showing an abnormal result. Increased -when there is active involvement of large joints or widespread bone erosion

    Top of panel Close
  • Camouflage

    a way of hiding things by making them look like part of the surrounding area. 

    Top of panel Close
  • Carbuncles

    are large boils with multiple openings which usually appear where the skin is thick in particular the back of the neck. They can reach the size of an apple and cause severe pain, fever and general feeling of being unwell.

    Top of panel Close
  • Cardiovascular

    pertaining to the heart and blood vessels

    Top of panel Close
  • Cardiovascular disease

    any abnormal condition characterised by dysfunction of the heart and blood vessels

    Top of panel Close
  • Cataracts

    are normally associated with older people when the lens clouds over preventing light from reaching the retina. In younger people they can result from an injury, taking certain medication, long-standing inflammation, or illnesses such as diabetes.

    Top of panel Close
  • Cell

    an organism that contains all the genetic information required to make a life form

    Top of panel Close
  • Chilblains

    appear as hot, red, swollen patches of itchy skin on toes, feet, fingers and hands after exposure to extreme cold and/or moisture. Normally they will go of their own accord after a few days but occasionally they can become chronic causing discoloration of the skin and painful blisters containing blood stained fluid followed by ulceration.

    Top of panel Close
  • Chinese herbal medicine

    is an integrated system of primary healthcare that also utilises herbal medicine, massage, exercise and diet. Based on the concepts of yin and yang, the tradition holds that energy known as qi (pronounced chee) or “life energy” flows through the body’s meridians (a network of invisible channels through the body). If the flow of qi in the meridians becomes blocked or there is an inadequate supply of qi, then the body goes out of balance and fails to maintain harmony and order, and disease or illness follows.This can result from stress, overwork, poor diet and environmental conditions.

    Top of panel Close
  • Chiropodist

    a healthcare professional who diagnoses and treats disorders of the feet is known as a Chiropodist. Podiatrists (podiatry) and chiropodists (chiropody) complete a 4 year postgraduate educational program leading to a degree of Doctor of Podiatric Medicine The main use of Chiropractic is for musculoskeletal disorders such as neck, shoulder or other joint problems, spine and posture problems, as well as muscle problems, sciatica, RSI, sports injuries and it can also be useful in the treatment of migraine

    Top of panel Close
  • Chiropractic

    is concerned with mechanical disorders of the musculoskeletal system and the effects of these disorders on the nervous system and health in general.

    Top of panel Close
  • Cholesterol

    is a waxy, fat-like substance that is made in the body by the liver.There are two main types of cholesterol: HDL and LDL. Most cholesterol is LDL (low-density lipoprotein) cholesterol. LDL cholesterol is more likely to clog blood vessels because it carries the cholesterol away from the liver into the bloodstream, where it can stick to the blood vessels. HDL (high-density lipoprotein) cholesterol, on the other hand, carries the cholesterol back to the liver where it is broken down.

    Top of panel Close
  • Chronic

    a persistent and lasting disease or medical condition or one that has developed slowly. As apposed to acute, which is a disease with a rapid onset and/or a short course.

    Top of panel Close
  • Citrullin antibodies

    is a new and very specific test for rheumatoid arthritis.

    Top of panel Close
  • Climatotherapy

    sunlight can have a beneficial effect on psoriasis. Climatotherapy has been used in the Dead Sea, Israel, for many years. Because of its position at the lowest point on earth and the haze of minerals in the atmosphere over the Dead Sea, burning rays of short wavelength UVB light are filtered out, allowing more exposure to longer wavelength therapeutic UVB rays.

    Top of panel Close
  • Clinical trial

    investigational studies of new treatments, new uses of existing treatments, and new screening methods to detect disease.

    Top of panel Close
  • Cluster

    to form a small group.

    Top of panel Close
  • Coal tar bath

    coal tar solution is added to bath water for great coverage and penetration, used to treat the scaling, inflammation and itching of psoriasis and other skin disorders

    Top of panel Close
  • Coeliac disease

    is a rare condition where the lining of the small intestine is damaged by gluten (a protein found in wheat, rye and certain other cereals).

    Top of panel Close
  • Cognitive

    pertaining to the mental processes of comprehension, judgment, memory, and reasoning, as contrasted with emotional processes.

    Top of panel Close
  • Colour therapy

    uses coloured rooms, light bulbs and other methods to impart mental and spiritual balance.Therapists can provide recommendations for incorporating certain colours into one's home, wardrobe and other places to promote health and healing

    Top of panel Close
  • Combination therapies

    sometimes clinicians will prescribe a product containing one or more active ingredients with different functions. This may be in order to simplify the number of treatments being applied at any one time or because the agents combined together have been shown to act better than when used independently.

    Top of panel Close
  • Complementary therapies

    a variety of treatments, outside the scope of conventional medical practice, and used alongside standard treatments for example herbal remedies, massage, acupuncture, reflexology, aromatherapy, shiatsu etc.

    Top of panel Close
  • Compliance

    is much the same as adherence – whether a patient carries out what they are advised.

    Top of panel Close
  • Condom

    is a flexible sheath that covers the penis and prevents semen from entering the vagina in sexual intercourse and is used to prevent transmission of an infection and conception.

    Top of panel Close
  • Contagious

    spread by direct or indirect contact between people (non-contagious: incapable of being transmitted from person to person).

    Top of panel Close
  • Contraception

    the word given to a process or technique for preventing pregnancy by means of a medication, device, or method that blocks or alters one or more of the processes of reproduction in such a way that sexual union can occur without impregnation.

    Top of panel Close
  • Contract research organisation

    carries out the research on behalf of a pharmaceutical company.

    Top of panel Close
  • Costochondritis

    is an inflammation and tenderness of the cartilage that attaches the front of the ribs to the breastbone. The worst pain is normally between the breast and the upper abdomen and is often more noticeable when sitting or laying down. Stress may aggravate this condition. Any of the costochondral junctions may be affected, and more often than not more than one site is involved. The inflammation can involve cartilage areas on both sides of the sternum, but more often than not is on one side only. Costochondritis should be distinguished from Tietze Syndrome, which is an inflammation involving the same area of the chest, but also includes swelling.

    Top of panel Close
  • Counselling

    is a process where clients are helped in dealing with their personal and interpersonal conflicts by a third party therapist.

    Top of panel Close
  • Craniosacral therapy

    is a gentle, hands-on method of treatment, which involves a health practitioner applying very light touch to the body (usually no greater than 5 grams) to evaluate and enhance the functioning of a body system called the craniosacral system.

    Top of panel Close
  • Creams

    are an emulsion of oil and water whipped together.They are well absorbed, less greasy.

    Top of panel Close
  • Creatinine clearance test

    is a test which is done on a 24 hour urine sample and a blood sample as a measure of kidney function.

    Top of panel Close
  • Crystal therapy

    the aim of this type of therapy is to restore wholeness, balance and health on levels of emotions, mind, spirit as well as the physical body.

    Top of panel Close
  • CTIMP

    clinical trial of an investigational medicinal product.

    Top of panel Close
  • Ciclosporin

    a prescription drug that decreases the body's immune response, used in the treatment of psoriasis.

    Top of panel Close
  • Cysts

    a sac or pouch within the body, which is usually filled with fluid.

    Top of panel Close
  • Cytokine

    messengers that carry biochemical signals to regulate local and systemic immune responses, inflammatory reactions, wound healing, formation of blood cells, and any other biological processes. In psoriasis, cytokines carry messages that promote overly rapid development of skin cells.

    Top of panel Close
  • Deformity

    a condition of being distorted, disfigured, flawed, malformed, or misshapen, which may affect the body in general or any part of it.

    Top of panel Close
  • Dentist

    is a person trained to treat, fill and extract teeth.

    Top of panel Close
  • Dermatitis

    is  an inflammation of the skin which can be as a result of an infection or a substance that has come into contact with the skin. Classified as acute, sub-acute or chronic depending on the severity.

    Top of panel Close
  • Dermatologist

    a physician specialising in disorders of the skin.

    Top of panel Close
  • Dermatology

    the study of the skin, including its anatomic, physiologic, and pathologic characteristics and the diagnosis and treatment of skin disorders.

    Top of panel Close
  • Dermatology Life Quality Index (DLQI)

    is a simple ten point questionnaire, which is used for more than 30 different skin conditions. It is the most frequently used questionnaire in controlled trials in dermatology.

    The ten questions include the following areas:

    • Symptoms and feelings
    • Daily activities
    • Leisure
    • Work and school
    • Personal relationships
    • Treatment

    These are assigned a score and once added together give a total DLQI.

    Top of panel Close
  • Dermatomyositis

    inflammation of the muscles normally accompanied by a rash over the eyelids, cheeks, chest and knuckles. Muscles become weak, stiff and painful and the skin over these muscles feels thicker than normal. There may also be bouts of nausea, weight loss and fever.

    Top of panel Close
  • Dermis

    the deep layer of skin.

    Top of panel Close
  • Detatched retinas

    are rare but sight-threatening. They occur when the retina becomes separated from the underlying tissue.

    Top of panel Close
  • Dexa scan

    is the best measurement of bone mineral density. Inflammatory spondylitis found in some patients with arthropathy may be accompanied by reduced bone density in the vertebrae particularly.

    Top of panel Close
  • Disability

    the loss, absence, or impairment of physical and or mental fitness.

    Top of panel Close
  • Disease

    is an unhealthy condition or illness.

    Top of panel Close
  • Disease-Modifying Anti-Rheumatic Drugs (DMARDs)

    if a patient has persistent inflammation in several joints for longer than six weeks then the doctor might prescribe a medication called a Disease Modifying anti-rheumatic Drug or DMARD (pronounced DeeMard). They are usually prescribed in addition to anti-inflammatory NSAIDs as the NSAID is designed to reduce the day-to-day inflammation and the DMARD slows down the biological processes that cause the persistent inflammation.

    Top of panel Close
  • DNA

    antibodies to DNA are the most specific and reliable test for the diagnosis of systemic lupus erythematosus and are rarely found in psoriatic arthropathy whereas the screening test for anti-nuclear antibody is occasionally found positive but usually has no significance.

    Top of panel Close
  • Effusion

    the name given to the collection of fluid in a joint.

    Top of panel Close
  • electronic Medicines Compendium (eMC)

    electronic Medicines Compendium (eMC) contains up to date, easily accessible information about medicines licensed for use in the UK. The eMC has more than 7,000 documents, all of which have been checked and approved by either the UK or European government agencies which license medicines. These agencies are the UK Medicines and Healthcare products Regulatory Agency (MHRA) and the European Medicines Agency (EMEA).

    Top of panel Close
  • Emollients

    soothe,smooth and hydrate the skin and are indicated for all dry or scaling disorders. Their effects are short-lived and they should be applied frequently even after improvement occurs.

    Top of panel Close
  • ENA

    antibodies to extractable nuclear antigens are looked for in patients with connective tissue diseases such as systemic lupus erythematosus and are helpful in predicting which organs are likely to be affected and indicating a more specific diagnostic category.

    Top of panel Close
  • Enthesopathy

    is a condition that affects the entheses such as inflammation of the entheses. The entheses are sites of tendinous or ligamentous attachment to the bone. Enthesopathy may be due to an inflammatory condition such as psoriatic arthritis or a condition due to injury or overload such as plantar fasciitis.

    Top of panel Close
  • Enthesis

    the junction between bone and ligament or bone and muscles.

    Top of panel Close
  • Enthesitis

    inflammation of this junction is commonly found in psoriatic arthritis.

    Top of panel Close
  • Enthesopathy

    is a condition that affects the entheses such as inflammation of the entheses.The entheses are sites of tendinous or ligamentous attachment to the bone. Enthesopathy may be due to an inflammatory condition such as psoriatic arthritis or a condition due to injury or overload such as plantar fasciitis.

    Top of panel Close
  • Epidermis

    the outer layer of skin.

    Top of panel Close
  • Erythema

    redness of the skin which is caused by congestion of the tiny blood vessels (capillaries) near the surface.The blood vessels may become dilated and congested with blood as the result of many different factors.

    Top of panel Close
  • Erythroderma

    an abnormal reddening, flaking and thickening of the skin, affecting a wide area of the body.

    Top of panel Close
  • Erythrodermic

    intense scaling and inflammation of the skin.

    Top of panel Close
  • Erythrodermic psoriasis

    psoriasis characterised by severe redness, scaling and shedding of the skin.

    Top of panel Close
  • ESR

    traditional test for inflammation - not specific for arthritis and may be normal despite it.

    Top of panel Close
  • Ethics committee

    make decision on if research is justified and that it is carried out in a manner which is deemed appropriate.

    Top of panel Close
  • Exanthema

    a skin eruption which occurs as a symptom of an acute viral disease, as in scarlet fever or measles.

    Top of panel Close
  • Exercise

    the performance of any physical activity for the purpose of condition the body, improving health, or maintaining fitness or as a means of therapy for correcting a deformity or restoring the organs and body functions to a sate of health. An action skill or manoeuvre that causes muscle exertion and is performed repeatedly to developer strengthen the body or any of its parts. To use a muscle or part of the body in a repetitive way to maintain or develop its strength.

    Top of panel Close
  • Exfoliation

    removing dead cells from the skin’s surface.

    Top of panel Close
  • Facet joints

    the small joints extending throughout the spine which slide up and down in movement and a source of pain when inflamed.

     

    Top of panel Close
  • Fatigue

    a condition marked by extreme tiredness and inability to function due lack of energy. Fatigue may be acute or chronic.

    Top of panel Close
  • Fever

    (from the Latin word febris) is a term used to describe a body temperature above the normal average of 37oC (98.6oF) It is one of the body’s defence mechanisms against bacterial and viral infection.Early symptoms include a feeling of heat and discomfort, flushed skin, increased pulse and respiration and sometimes insomnia. The most effective drug to control fever is a non-steroidal anti-inflammatory drugs such as aspirin or ibuprufen.

    Top of panel Close
  • Flexures

    the areas where the limbs bend, bringing together two surfaces, for example, the front of the elbows and the back of the knees.

    Top of panel Close
  • Flower therapy

    is a form of energy medicine using extracts of flowers that can be used in conjunction with traditional counselling. It offers an alternative treatment for daily stress, mild to moderate mood concerns, fears and anxieties and other emotional issues.

    Top of panel Close
  • Flu (influenza)

    is a viral infection of the respiratory tract although symptoms are normally present elsewhere in the body. It is transmitted through droplets from infected people either during coughing, sneezing and also speaking. There is normally an incubation period of up to four days before the symptoms appear. Symptoms vary but can include some or all of the following. Fever, chills, cough, stuffiness, runny nose, sore throat, aches and pains all over the body, headache, loss of appetite, nausea, weakness and depression.As flu is a viral infection there is no specific drug treatment but bed rest and simple analgesics may help. Recovery periods are normally within a week.

    Top of panel Close
  • Folic acid

    is given to patients on methotrexate, as it reduces the likelihood of mouth ulcers and blood count abnormalities.

    Top of panel Close
  • Follicle

    is a pore in the skin from which hair grows.

    Top of panel Close
  • Folliculitis

    inflammation of the hair follicles of the skin or the scalp usually caused by bacterial infection.

    Top of panel Close
  • Frostbite

    a condition caused by the direct effect of freezing on the tissues, made worse by the lack of blood to the area. The skin firstly takes on a pallid colour which progresses to a reddish violet and finally to black as the tissue dies.

    Top of panel Close
  • Fumaric acid esters (FAE)

    are chemical compounds derived from the unsaturated dicarbonic acid fumaric acid and have been used in treatment of psoriasis since 1950s. Side effects include flushing of the skin. Tolerance is limited by gastrointestinal issues.

    Top of panel Close
  • Gamma-glutamyl transferase (GGT)

    Blood test for a protein made in the liver, particularly sensitive to alcohol overuse, but found in other causes of liver dysfunction. Patients with high results are not safe to take methotrexate without careful evaluation.

    Top of panel Close
  • Gene

    The material that forms the biologic code for all life forms.

    Top of panel Close
  • General Practitioner (GP)

    is a healthcare professional who treats all kinds of illnesses and health related problems. He or she is the first doctor that people would see when they are ill. This is also known as primary care.

    Top of panel Close
  • Generic or non-proprietary

    products that are in the public domain and anyone can produce or distribute. These poducts are not protected by trademark or patent or copyright.

    Top of panel Close
  • Genital

    The sex, or reproductive organs visible on the outside of the body. Also known as the genitalia.

    Top of panel Close
  • Germ

    is a tiny organism that can cause diseases.

    Top of panel Close
  • Glaucoma

    is the name given to a group of eye diseases in which the optic nerve at the back of the eye is slowly destroyed. Untreated glaucoma leads to permanent damage of the optic nerve which can progress to blindness.

    Top of panel Close
  • Glucose

    the sugar found in the blood which the brain and the muscles use as fuel. 

    Top of panel Close
  • Glucose tolerance test

    test involving taking a dose of glucose followed by a series of blood tests to see how much has appeared in the blood over a period of hours and used to confirm diagnosis of diabetes.Useful in patients on long-term steroid treatment.

    Top of panel Close
  • Glycated Haemoglobin

    a test done on blood in diabetes to check on long term control.

    Top of panel Close
  • Goeckerman regimen

    patients with severe or disabling psoriasis may go to hospital or psoriasis treatment centres for concentrated treatment with UVB and topical coal tar. This is known as the Goeckerman regimen and usually takes at least three or four weeks of daily treatment.

    Top of panel Close
  • Gold (sodium aurothiomalate)

    injections (intramuscular) are sometimes used since 1930s to reduce the inflammation in joints and decrease pain, swelling and stiffness in psoriatic arthritis.

    Top of panel Close
  • GRAPPA (Group for Research and Assessment of Psoriasis and Psoriatic Arthritis)

    is organised exclusively for non-profit, educational, and scientific purposes, specifically to facilitate sharing of information related to psoriasis and psoriatic arthritis, networking among different medical disciplines that see psoriasis and psoriatic arthritis patients and to enhance research, diagnosis and treatment of psoriasis and psoriatic arthritis.

    Top of panel Close
  • Grenz ray

    involves exposing the skin to low-energy, non-penetrative electromagnetic radiation. It is used in inflammatory skin conditions such as psoriasis as an option if other therapies have failed. There a number of studies that have looked at this therapy. The largest included 5739 patients, of which 24% of all psoriasis patients had been treated with Grenz rays.There is divided opinion on the use of the therapy and in the UK, it has been suggested that it no longer has a place in the treatment pathway as newer therapies have superseded it.

    Top of panel Close
  • Guttate

    a term that is used to describe lesions on the skin that are shaped like drops of water.

    Top of panel Close
  • Guttate psoriasis

    psoriasis characterised by red, drop-like dots on the skin.

    Top of panel Close
  • Headache

    the most common type of headache is the tension headache which is caused by contractions of the muscles of the back of the neck and the scalp. The headache is relieved when the muscle contractions cease. This can be helped along by taking an analgesics such as paracetamol. Headaches can also follow from a head injury caused either because of the tenderness at the point of injury or because of the contraction of muscles around it. These types of headaches are known as vascular or delusional headaches.Headaches are also associated with high blood pressure (hypertension).

    Top of panel Close
  • Healthcare professionals

    is a term used for a person who is qualified to provide health care to others.It includes general practitioners (GPs), physicians, surgeons, nurses, pharmacists, occupational therapists, psychologists, dermatologists, rheumatologists, chiropractors, osteopaths, physiotherapist, podiatrist, chiropodist, optometrists, paramedics, dentist, and a wide variety of other individuals regulated and/or licensed to provide some type of health care.

    Top of panel Close
  • Helper T-cells

    cells that travel through the blood looking for antigens, when one is encountered they trigger other immune cells to attack.

    Top of panel Close
  • Herbal medicine

    is where a pharmaceutical preparation contains at least one active ingredient extracted from plant sources.

    Top of panel Close
  • Hereditary

    pertaining to a characteristic, condition, or disease transmitted from parent to offspring; inborn; inherited.

    Top of panel Close
  • Herpes

    a highly infectious virus which causes crusted sores most commonly around the lips and mouth (cold sores) and the genitals. It begins with itching of the skin followed by redness and swelling which turn to fragile blisters which rupture to excude a sticky fluid which rapidly crusts over.

    Top of panel Close
  • Hives (urticaria)

    a skin eruption or red and white raised patches on the skin similar to that caused by nettles.The patches cause great irritation and are normally seen on the trunk and on the face.

    Top of panel Close
  • HLA B27 (Human Leukocyte Antigen B27)

    is associated with a certain set of autoimmune diseases including psoriatic arthritis.

    • A blood test is often carried to establish a diagnosis particularly in ankylosing spondylitis.
    • In ankylosing spondylitis (AS). 90% of patients will have a positive test for HLA B27.
    • In psoriatic arthritis (PsA) 20% of patients will have a positive test for HLA B27.
    • 50% of HLA B27 positive tests will have spinal disease (spondylopathy)
    • 7% percent of the general population have the HLA-B27 gene.
    Top of panel Close
  • Homoeopathy (sometimes spelt homeopathy)

    is a system of medicine founded by Samuel Hahnemann at the end of the 18th Century. It is based on the theory that diseases are curable by those drugs which produce effects on the body similar to symptoms caused by the disease. (similia similibus antur).

    Top of panel Close
  • Hormones

    a complex chemical substance produced in one part or organ of the body that initiates or regulates the activity of an organ or a group of cells in another part.

    Top of panel Close
  • Housemaid's knee or bursitis

    is an inflammatory condition of the bursa in front of the knee cap, often mistaken for joint disease.

    Top of panel Close
  • Hydrotherapy

    is supervised exercise in a warm pool. The physiotherapist uses the properties of water to help ease stiff joints and strengthen weak muscles. Hydrotherapy may include continuous tub baths, wet sheet packs or shower sprays.

    Top of panel Close
  • Hyperkeratosis

    thickening of the nail.

    Top of panel Close
  • Hyperostosis

    means abnormal excessive growth of bone.

    Top of panel Close
  • Hypertension

    a term meaning blood pressure that is above the normal range

    Top of panel Close
  • Hypnotherapy

    is the use of a state of relaxation varying from very light to deep and is used for treating such conditions as addictions, anxiety, depression, obesity, irritable bowel syndrome, phobias and stress.

    Top of panel Close
  • Hypoglycaemia

    low blood sugar.

    Top of panel Close
  • Ichthyosis

    a hereditary condition which is characterised by thick scale and very dry skin. Mild cases may pass off as dry skin, but in severe cases the skin looks like fish skin or alligator hide. The dry, scaly skin is usually most severe over the legs but may also involve the arms, hands, and middle of the body. Persons with this condition may also have many fine lines over the palm of the hand.

    Top of panel Close
  • Ichthyotherapy

    is when a wound or condition is cleansed by the use of fresh water or marine organisms such as a fish. In psoriasis the most common scenario is the use of the Doctor Fish of Kangal found in the fresh water springs of Turkey, Syria, Iraq and Iran.

    Top of panel Close
  • Immune system

    the biochemical complex that protects the body against infections and other foreign bodies that lead to illness.

    Top of panel Close
  • Immunomodulatory drugs

    drugs that alter the function of the immune system.

    Top of panel Close
  • Investigational medicinal product (IMP)

    is the name of a new medicine in development.IMP: Investigational medicinal product is the name of a new medicine in development.

    Top of panel Close
  • Impetigo

    is a skin infection caused by the bacterium staphylococcus aureus or streptococcus pyogenes. Impetigo causes spots containing pus (pustules) that become crusty yellow sores. It often occurs on the face around the mouth and nose. It can be treated with antibiotic creams or tablets.

    Top of panel Close
  • Infection

    is the invasion of the body by pathogenic organisms and their subsequent multiplication with this body.

    Top of panel Close
  • Inflammation

    reaction by tissue, for example skin, in response to infection or injury, usually involving reddening and swelling.

    Top of panel Close
  • Information Standard Scheme (The)

    was developed by the Department of Health to help the public identify trustworthy health and social care information easily. At the heart of the scheme is the standard itself – a set of criteria that defines good quality health or social care information and the methods needed to produce it. To achieve the standard, organisations have to show that their processes and systems produce information that is:

    • accurate
    • impartial
    • balanced
    • evidence-based
    • accessible
    • well-written.

    The assessment of information producers is provided by independent certification bodies accredited by The United Kingdom Accreditation Service (UKAS). Organisations that meet The Standard can place the quality mark on their information materials and their website - a reliable symbol of quality and assurance. PAPAA became a Certified Member of the Information Standard in April 2011.

    Top of panel Close
  • Informed consent

    the process by which a volunteer for a clinical trial agrees to participate after being fully informed regarding purposes of the trial, risks and benefits associated with participation in the trial, and whether volunteers will be randomised to receive treatment or placebo.

    Top of panel Close
  • Injection

    the act of forcing a liquid into the body by means of a needle and syringe.

    Top of panel Close
  • Insomnia

    sleep problems characteristically association with difficulty falling asleep and frequently waking during the night.

    Top of panel Close
  • Insulin

    acts by enabling the muscles and other tissues which require sugar for their actvity to take up this substance from the blood.The lack of insulin or the inability to produce enough insulin is found in people with diabetes.

    Top of panel Close
  • Intercurrent illnesses

    different disease or co-morbility .

    Top of panel Close
  • International Psoriasis Council (IPC)

    is a global organisation founded in August 2004. IPC has created programs, events, and materials that have provided a forum for psoriasis experts and health professionals to share knowledge, experiences, and insights toward optimising understanding and treatment of psoriasis.

    Top of panel Close
  • Interphalangeal

    any of the joints between the phalanges of the fingers or toes.

    Top of panel Close
  • Intertrigo

    inflammation and chafing of the skin caused by two surfaces rubbing together. Normally occurs on the inner thighs, armpits, underside of the breasts, folds of the abdomen and between fingers and toe. There may also be scales and blisters and the affected skin may have an odour.

    Top of panel Close
  • Intravenous infusion

    technique of giving medicines via a vein.

    Top of panel Close
  • Inverse psoriasis

    also known as flexural psoriasis and intertriginous psoriasis which is characterised by smooth, inflamed lesions in body folds.

    Top of panel Close
  • Iridology

    is the analysis of patterns and structures in the iris of the eye which locates areas and stages of inflammation throughout the body. It reveals body structure, inborn strengths and weaknesses, health levels, and changes that take place in a person's body according to their way of life.

    Top of panel Close
  • Jaundice

    a yellow discolouration of the skin, mucous membranes, and the eyes caused by greater than normal amounts of bilirubin in the blood. Because people with dark skin sometimes have yellow tinged sclera the hard palate of the mouth is often the best place to assess for jaundice. People with jaundice may experience nausea, vomiting, and abdominal pain and may pass dark urine and clay coloured stools.

    Top of panel Close
  • Joint

    is the meeting-place between different parts of the skeleton.

    Top of panel Close
  • Joint inflammation

    a condition in which a becomes reddened, swollen, hot, and often painful, especially as a reaction to injury or infection.

    Top of panel Close
  • Keratinocyte

    a type of skin cell making up over 95% of the epidermis, accelerated growth of these cells leads to the development of psoriasis lesions.

    Top of panel Close
  • Keratitis

    inflammation of the cornea (the transparent front layer of the eye).

    Top of panel Close
  • Keratolytic

    an agent that promotes the shedding of the epidermis at regular intervals.

    Top of panel Close
  • Keratosis

    a skin condition where patches of rough skin appear on the upper arms, thighs, and buttocks. It is sometimes also known as keratosis pilaris or 'chicken skin'

    Top of panel Close
  • Killer T-cells

    cells in the immune system that actively target and destroy cells perceived as foreign.

    Top of panel Close
  • Kinesiology

    uses simple, safe, precise muscle testing procedures to find problem areas, to get to the cause of the problem and not just deal with the symptoms of a problem. Kinesiology uses massage, nutrition, energy reflexes, and counselling to balance holistically.

    Top of panel Close
  • Koebner’s phenomenon

    psoriatic lesions that appear at the site of injury, infection or other skin problem.

    Top of panel Close
  • Latex test

    very sensitive, but not very specific test for rheumatoid factor in the serum

    Top of panel Close
  • Latin prescription abbreviations

    what abbreviations mean on your prescription

    • a. c. = ante cibum (before food)  
    • b. d. = bis die (twice daily)  
    • o. d. = omni die (every day)  
    • o. m. = omni mane (every morning)  
    • o. n. = omni nocte (every night) 
    • p. c. = post cibum (after food)  
    • p. r. n. = pro re nata (when required)  
    • q. d. s. = quater die sumendum (to be taken four times daily)  
    • q. q. h. = quarta quaque hora (every four hours)  
    • stat = immediately  
    • t. d. s. = ter die sumendum (to be taken three times daily)  
    • t.i.d. = ter in die (three times daily)
    Top of panel Close
  • Lesions

    a wound or injury to the skin, for example, a patch of skin affected by psoriasis.

    Top of panel Close
  • Leucocytes

    a type of white blood cell involved in the immune system. White blood cells increased during infection. In psoriatic joint effusions leucocytes, rather than lymphocytes, show a particular increase in numbers. In rheumatoid arthritis lymphocytes usually predominate. In the blood lymphocytes are often found to be reduced in patients on immunosuppressive forms of treatment.

    Top of panel Close
  • Ligament

    one of many white shiny flexible bands of fibrous tissue binding joints together and connecting various bones and cartilages

    Top of panel Close
  • Likert scale

    is usually based on 5 points or questions with 1 = the best and 5 = the worst.
    A common example is:

    • 1 = Strongly agree
    • 2 = Agree
    • 3 = Neither agree or disagree
    • 4 = Disagree
    • 5 = Strongly disagree

    Sometimes a 4 point scale is used which is called a ‘forced choice’ and misses the middle point, therefore giving either agreement of disagreement.

    Top of panel Close
  • Linear IgA disease

    a very itchy rash with annular grouped vesicles. Histology shows a subepidermal blister and immuniofluorescene shows a linear band of IgA at the basement membrane

    Top of panel Close
  • Lotions or solutions

    are liquids that are easier to use on large areas of skin, especially where there is hair. Lotions also have a cooling effect.

    Top of panel Close
  • Lumbago

    a generalised term used to describe ailments affecting the muscles of the lower back.

    Top of panel Close
  • Lung fibrosis

    a rare complication of treatment with methotrexate predominantly in elderly women.

    Top of panel Close
  • Macrocytes

    red blood cells of increased size. May be found in patients treated with azathioprine, methotrexate or sulfasalazine.

    Top of panel Close
  • Macrophage

    cells that destroy foreign antigens and initiate T-cell formation, also called an ‘antigen-presenting cell’.

    Top of panel Close
  • Magnatherapy

    is an alternative form of treatment for the relief of pain. High density magnets draw fresh blood to the affected area which in turn stimulates blood flow which carries away toxic materials which cause the pain. This not only brings great relief from the pain but also speeds up the healing process.

    Top of panel Close
  • Mantoux test (or Mantoux screening test or Heaf test )

    is skin test for tuberculosis. Until 2005 to determine if the Bacillus of Calmette and Guérin (BCG) vaccine was needed. Patients who exhibit a negative reaction to the test may be offered BCG vaccination. Patients being offered biological treatments for psoriasis are recommended to have a Mantoux test. If they fit the criteria laid down in the British Association of Dermatologists guidelines for use of biological interventions in psoriasis. For the treatment of arthritis as recommended in Assessing, managing and monitoring biologic therapies for inflammatory arthritis. Guidance for rheumatology practitioners.

    Top of panel Close
  • Massage or rubbing

    is where, the surface of the body is rubbed, kneaded or pressed in order to stimulate the skin or deeper tissue with the use of fingers, hands or other equipment or appliances. Different types of massage can be gentle stroking to soothe (such as applying topical treatments) or vigorous methods to stimulate the circulation of blood.

    Top of panel Close
  • Melaena

    means a condition where the stools (faeces) are dark or black, due to bleeding from the stomach or higher part of the bowel.

    Top of panel Close
  • Melanoma

    is the most serious type of skin cancer. It begins in skin cells called melanocytes. Melanocytes are the cells that make melanin, which gives skin its color. When people spend time in the sunlight, the melanocytes make more melanin and cause the skin to tan. If the skin receives too much sunlight, the melanocytes may begin to grow abnormally and become cancerous. This condition is called melanoma. The first sign of melanoma is often a change in the size, shape, or color of a mole. But melanoma can also appear on the body as a new mole.

    Top of panel Close
  • Metatarsophangeol

    is sometimes called "pencil in cup". A characteristic radiographic feature of psoriatic arthritis. Other features include joint erosions, joint space narrowing, bony proliferation including periarticular and shaft periostitis, osteolysis including deformity and acro-osteolysis, ankylosis, spur formation, and spondylitis.

    Top of panel Close
  • Methotrexate (MTX)

    an agent prescribed for the treatment of moderate to severe psoriasis.

    Top of panel Close
  • MHRA (Medicines and Healthcare products Regulatory Authority)

    the body who regulate licensing of drugs used in humans.

    Top of panel Close
  • Moisturisers

    make the skin much more comfortable – they decrease the dryness, scaling, cracking, soreness and itching. They allow other active treatments (eg tar, vitamin D) to work more effectively.

    Top of panel Close
  • Moles

    a blemish on the skin which maybe present at birth or may develop over time. Moles are made up of clusters of naevus cells which contain the pigment melanin. They can be small or large, flat or raised, smooth, hairy or warty. They vary in colour from yellowish brown to black.

    Top of panel Close
  • Monoclonal antibody (MAb)

    antibodies created with biotechnology techniques in laboratories that are highly specific and ‘recognise’ and target only one molecule, such as a receptor, or antigen.

    Top of panel Close
  • MRI (magnetic resonance imaging)

    uses magnetic fields and radio signals to compose images of body slice by slice without using x-rays.

    Top of panel Close
  • Mucous

    the viscous, slippery secretions of mucous membranes and glands containing mucin, white blood cells, water, inorganic salts and exfoliated cells.

    Top of panel Close
  • Multidisciplinary team

    is a group of people each using their own specialised skills but working together as a team.

    Top of panel Close
  • Muscle

    is tissue that by its virtue has power of contraction.

    Top of panel Close
  • Musculoskeletal

    is a term relating to the bones and/or the muscles.

    Top of panel Close
  • Naturopathy

    is a system of medicine based on the healing power of nature. Naturopathy is a holistic system, meaning that naturopathic doctors try to find the cause of disease by understanding the patients body, mind, and spirit. Most naturopathic doctors use a wide variety of therapies and techniques (such as nutrition, herbal medicine, homoeopathy and acupuncture).

    Top of panel Close
  • NICE (The National Institute for Health and Care Excellence)

    is the independent organisation responsible for providing national guidance on the promotion of good health and the prevention and treatment of ill health.

    Top of panel Close
  • Non-contagious

    incapable of being transmitted from person to person.

    Top of panel Close
  • Non proprietary

    or generic products that are in the public domain and anyone can produce or distribute. These products are not protected by trademark or patent or copyright.

    Top of panel Close
  • NSAIDs

    Non-steroidal anti-inflammatory drugs

    Top of panel Close
  • Numbness

    loss of sensation in fingers, eg, in carpal tunnel syndrome, in toes in sciatica or generally in peripheral neuropathy and other neurological diseases. Seen occasionally as a drug side-effect.

    Top of panel Close
  • Nurse 

    is a healthcare professional who is trained to care for the sick.

    Top of panel Close
  • Nutrient 

    is something that provides nourishment for an organism to live. There are six main types: carbohydrates, proteins, fats, vitamins, minerals, and water.

    Top of panel Close
  • Nutritional therapy 

    is a system of healing based on the idea that food provides the medicine we need to obtain and maintain a healthy state. In other words our food is our medicine and our medicine is our food. Many disorders, ranging from fatigue, energy loss, insomnia and depression, to backache, skin complaints, asthma, and headaches can be relieved effectively with nutritional therapy.

    Top of panel Close
  • Obesity

    the word obesity means being so overweight that it's bad for your health. 

    Top of panel Close
  • Occupational therapist 

    works as part of a multidisciplinary team. They either work for the health service or for social services. The two services work slightly differently but occupational therapists are all concerned with promoting a persons independence in every task to give the best quality of life.

    Top of panel Close
  • Ointments 

    are greasy and tend to stay on the surface of the skin. Some contain substances that help them mix with water so they wash off more easily.

    Top of panel Close
  • OMERACT 

    stands for Outcome Measures in Rheumatology. It is an informal international network of working groups and gatherings interested in outcome measurement across the spectrum of rheumatology intervention studies. The Patient Liaison Group co-ordinates the participation of patients in the OMERACT Working Groups. OMERACT highly encourages the input of patient perspectives into all research groups. OMERACT holds Consensus Conferences every 2 years in various parts of the world.

    Top of panel Close
  • Onycholysis

    a severe form of the psoriatic nail dystrophy where the nail becomes detached from the underlying nail bed and a gap develops under the nail. When it starts there is a white or yellowish patch at the tip of the nail, and this then extends down to the cuticle.

    Top of panel Close
  • Onychomycosis

    a chronic but painless fungal infection of the nail caused by a number of fungal species.

    Top of panel Close
  • Optimum

    the best. The most favourable.

    Top of panel Close
  • Optometrist 

    is concerned with examining the eyes, testing sight, giving advice on visual problems, and prescribing and dispensing spectacles or contact lenses. Optometrists are also trained to recognise eye diseases.

    Top of panel Close
  • Oral

    preparations taken orally are taken by mouth whereas topical application of medicine is applied to the skin.

    Top of panel Close
  • Organism

    is any living thing whether plant or animal.

    Top of panel Close
  • Osteitis

    means inflammation of the bone.

    Top of panel Close
  • Osteopathy

    is a system of diagnosis and treatment, usually by manipulation, that focuses on musculoskeletal problems. Osteopaths believe that the problem lies with an impairment of blood supply.

    Top of panel Close
  • Osteopaths 

    use their hands both to diagnose and to treat abnormalities in the way the body is working

    Top of panel Close
  • OTC 

    is the abbreviation for over the counter (non prescription) which appears on licensed medicines. These are generally purchased at a pharmacy without a prescription as oppossed to POM (prescription only medicine).

    Top of panel Close
  • P

    is the abbreviation for pharmacy which appears on licensed medicines. These are only available from or dispensed by a pharmacist.

    Top of panel Close
  • Paediatrician

    a physician who specialises in the development and care of infants and children and in the treatment of their diseases.

    Top of panel Close
  • Paediatric

    pertaining to preventive and primary health care and treatment of children and the study of childhood diseases.

    Top of panel Close
  • Papillioma

    a benign tumour which resembles a wart and is normally found on the skin and in the membranes that line the intestinal and urinary tracts.

    Top of panel Close
  • Parakeratosis

    the process by which psoriatic skin cells continuously form and move upward to the skin surface faster than they can be incorporated into the skin, resulting in them scaling off.

    Top of panel Close
  • Paramedic

    is a person trained to assist medical professionals and to give emergency medical treatment normally outside a hospital setting.

    Top of panel Close
  • Parapsoriasis

    cutaneous skin disease that looks similar to psoriasis (hence para meaning near or similar to), but isn’t psoriasis. Scaly plaques may be evident.

    Top of panel Close
  • Pastes

    ointments in which powder is suspended.

    Top of panel Close
  • PCG   

    Primary Care Group.

    Top of panel Close
  • PCT

    Primary Care Trust.

    Top of panel Close
  • PDI

    Psoriasis Disability Index.

    Top of panel Close
  • Periarthritis

    is when inflammation is near to or outside of a joint.

    Top of panel Close
  • Petechiae

    red and purple spots on the skin approximately the size of a pinhead. They are formed by the escape of blood into the skin.

    Top of panel Close
  • Phalanges

    is the name given to the bones that are found in the fingers or toes.

    Top of panel Close
  • Pharmaceutical company

    these are commercial companies who research and develop drugs which are used to treat conditions in humans.

    Top of panel Close
  • Pharmacist 

    is a healthcare professional who is trained to prepare medicines.

    Top of panel Close
  • Phototherapy

    treatment with artificial ultraviolet light.

    Top of panel Close
  • Photo-chemotherapy

    when light therapy and drug therapy are used in combination. Patients with psoriasis that does not respond to or is too widespread for topical treatments are candidates for phototherapy. This involves exposing the skin to wavelengths of UV light, which has a therapeutic benefit in psoriasis. Phototherapy is a standard treatment for patients with moderate to severe psoriasis who have not responded to topical therapies.

    Top of panel Close
  • Physician

    is a healthcare professional who is not a surgeon.

    Top of panel Close
  • Physiotherapy

    the treatment of disorders with physical agents and methods such as massage, manipulation, therapeutic exercises, cold, heat, hydrotherapy and light.

    Top of panel Close
  • PIL

    Product Information Leaflet is required to be included in any medicine package and contains information about what the product is for, dosages and side effects etc.

    Top of panel Close
  • Pitting

    small, punctuate indentations in fingernails or toenails often as a result of psoriasis

    Top of panel Close
  • Placebo

    an inactive drug with no medicinal value, used as method of ‘control’ in clinical trials.

    Top of panel Close
  • Plantar fasciitis

    means inflammation of the plantar fascia. The plantar fascia is a strong band of tissue (similar to a ligament) that stretches from the heel to the middle bones of the foot.

    Top of panel Close
  • Plaque

    a flattish, raised, scaly patch on the skin more than 2 cm across and formed by psoriasis.

    Top of panel Close
  • Plaque psoriasis

    is characterised by red, silvery-white, scaly skin lesions, accounting for about 80 percent of all cases.

    Top of panel Close
  • Platelets

    are the smallest cells in the blood formed in the red bone marrow and some are stored in the spleen.

    Top of panel Close
  • Podiatrist 

    (sometimes known as a chiropodist) is someone who cares for the feet.

    Top of panel Close
  • POM

    is the abbreviation for prescription only medicine which appears on licensed medicines. These are generally prescribed by a doctor or similarly qualified individual, and cannot be bought legally in the UK without a prescription.

    Top of panel Close
  • Pore

    is a small opening in the skin allowing moisture to pass in or out.

    Top of panel Close
  • Prurigo

    a  chronic inflammatory eruption of the skin which is normally accompanied by small whitish spots and severe itching.

    Top of panel Close
  • Pruritus

    itching of the skin around the anus or the vulva

    Top of panel Close
  • PsARC

    is the only measure developed specifically for people with psoriatic arthritis.

    The PsARC comprises:

    • A patient global self-assessment on a 0–5 Likert scale
    • A physician global assessment on a 0–5 Likert scale, with improvement defined as a decrease by at least 1 unit, and worsening defined as an increase by at least 1 unit
    • A tender joint score
    • A swollen joint score with improvement defined as a decrease of at least 30%, and worsening defined as an increase of at least 30%.
    Top of panel Close
  • PsARC response

    is defined as an improvement in at least two of the four measures, one of which must be the joint tenderness or swelling score, with no worsening in any of the four measures.The PsARC does not include an assessment of psoriasis.

    Top of panel Close
  • Psoriatic arthritis

    a genetically driven autoimmune disease affecting large and small joints that occurs in less than 10 percent of psoriasis patients

    Top of panel Close
  • Protocol

    set of rules to be followed.

    Top of panel Close
  • Psychologist

    is someone who has made a special study of psychology.

    Top of panel Close
  • Psychology

    is the study of the mind and how it works.

    Top of panel Close
  • Pustular

    pus filled lesions and intense scaling

    Top of panel Close
  • Pustular psoriasis

    characterised by pus-like blisters on the skin usually occuring on the hands or feet.

    Top of panel Close
  • Pustulosis

    is an inflammatory skin condition typically on the palms of the hands and/or the soles of the feet. With large fluid-filled blisters (pustules). The skin of these areas peels and flakes (exfoliates).

    Top of panel Close
  • PUVA (psoralen+ultraviolet A)

    is a form of photochemotherapy which combines a photosensitizing medication (psoralen) with long wave ultraviolet A light UVA which is known as PUVA. On its own UVA light is usually too week to be an effective treatment in psoriasis, however, when combined with a photosensitiser it becomes very effective for psoriasis and several other skin conditions.

    Top of panel Close
  • Quality-adjusted life year (QALY)

    an index of survival that is adjusted to account for patient's quality of life during this time.

    Top of panel Close
  • Qualitative research

    is used to help us understand how people feel and why they feel as they do. It is concerned with collecting in-depth information asking questions such as why do you say that?. Samples tend to be smaller compared with quantitaive projects that include much larger samples. Depth interviews or group discussions are two common methods used for collecting qualitative information.

    Top of panel Close
  • Quantitative research

    is used to measure how many people feel, think or act in a particular way. These surveys tend to include large samples - anything from 50 to any number of interviews. Structured questionnaires are usually used incorporating mainly closed questions - questions with set responses. There are various vehicles used for collecting quantitative information but the most common are on-street or telephone interviews.

    Top of panel Close
  • Queen Test

    quality question devised by a distinguished hospital architect and pioneer of operational research in hospitals.The question is: If we were doing this for the Queen, is this how we would do it.

    Top of panel Close
  • Radionics

    is a technique of healing using extrasensory perception (e.s.p.). It is not directed at the physical body so much as at the energy fields around it. The patient can be with the practitioner or many miles away - distance is irrelevant.

    Top of panel Close
  • Rash

    a group of spots or an area of red, inflamed and normally itchy skin which can be localised in one part of the body or involve extensive areas.

    Top of panel Close
  • Raynaud's phenomenon

    is a condition where the blood vessels that supply blood to the skin narrow reducing blood flow to the hands.

    Top of panel Close
  • Reactive arthritis

    is caused by bacteria travelling through the body to the joints between bones.

    Top of panel Close
  • Rebound

    recovery from illness.

    Top of panel Close
  • Receptor

    structures on the surface of cells that serve as docking sites for other cells or signalling molecules to relay information or trigger a reaction.

    Top of panel Close
  • Reflexology

    maps out the reflexes on the hands and feet to all the organs and the rest of the body. By applying acupressure and massage-like techniques to these reflex points, the related body parts are positively affected, and blood, nerve and lymphatic systems are rejuvenated thus improving supply.

    Top of panel Close
  • Reiki

    incorporates elements of other alternative healing practices such as spiritual healing, aromatherapy, auras, crystals, chakra balancing, homoeopathy, meditation and naturopathy. It involves the transfer of energy from practitioner to patient to improve the body’s natural ability to heal itself through the balancing of energy.

    Top of panel Close
  • Remission

    the period during which the symptoms of a disease decrease or subside.

    Top of panel Close
  • Repetitive strain injury (RSI)

    is used to describe a range of painful conditions of the muscles, tendons and other soft tissues.

    Top of panel Close
  • Retinoids

    Vitamin A derivatives used in the prevention and treatment of various skin problems.

    Top of panel Close
  • Retrospective study

    looks back and considers the vulnerability to potentional risks or safety factors in respect of the result that is demonstrated at the beginning of the study.

    Top of panel Close
  • Rheumatism

    is a general term applied to a group of diseases, which affect joints, muscles and other parts.

    Top of panel Close
  • Rheumatoid arthritis

    is a condition which causes pain, swelling and inflammation in the joints.

    Top of panel Close
  • Rheumatologist

    is a specialist in the treatment of musculoskeletal disease and systemic autoimmune conditions commonly referred to as rheumatic diseases. 

    Top of panel Close
  • Rheumatology

    the study of disorders characterised by inflammation, degeneration, or metabolic derangement of connective tissue and related structures of the body. These disorders are sometimes referred to collectively as rheumatism.

    Top of panel Close
  • Ringworm (tinea)

    a group of fungus infections of the skin, hair, toenails and fingernails. Ringworm usually causes reddened and scaly patches on the skin, which form in an irregular ring shape with a slightly raised edge. The patches may be very itchy.

    Top of panel Close
  • Rodent ulcer

    a chronic ulcer arising from a tumour normally present on the face or nose of elderly people.

    Top of panel Close
  • Rosacea

    a chronic disease where the skin is coloured red or pink as a result of the dilation of tiny blood vessels near the surface of the skin normally on the nose, forehead, cheeks and chin.

    Top of panel Close
  • Sacroiliac

    pertaining to the part of the skeletal system that includes the sacrum and the ilium bones of the pelvis.

    Top of panel Close
  • Sacroiliitis

    inflammation of the sacroiliac joint.

    Top of panel Close
  • Sacrum

    the composite bone at the base of the spine, forming the back of the pelvis.

    Top of panel Close
  • Salicylic acid

    is a chemical that helps remove scale on lesions. This then allows topical medications to better penetrate the skin.

    Top of panel Close
  • SAPHO

    Syndrome Acne-Pustulosis-Hyperostosis-Osteitis. The syndrome has common conditions together which include synovitis, acne, hyperostosis, pustulosis and osteitis

    Top of panel Close
  • Scabies

    a skin infection caused by the infestation of mites which burrow into the skin and lay their eggs. The burrowing causes intense itching.

    Top of panel Close
  • Scales

    thin flakes on the skin surface.

    Top of panel Close
  • Scleritis or 'hot eye'

    is sometimes associated in people with inflammatory arthritis, the symptoms are an inflammation of the white outer coating of the eye known as the sclera.Treatment with NSAIDs (nonsteroidal anti-inflammatory drugs), such as ibuprofen, are used for pain relief. Corticosteroids (oral) and an eye solutions are used to treat scleritis. Antibiotics may be prescribed as well. Using standard eye drops will not treat the condition.

    Top of panel Close
  • Scleroderma

    a rare disease which produces hardening of the skin which becomes smooth, shiny and tight. The skin of the face may shrink so much that it becomes difficult to open the mouth fully.

    Top of panel Close
  • Sebaceous cyst

    a term used for large, smooth modules under the skin which are most commonly found on the scalp, face, ear and genitals. The cyst contains a smooth yellow cheesy material.

    Top of panel Close
  • Seborrhoeic dermatitis or seborrhoea

    are names given to a group of diseases of the skin, in which the sebaceous oil-forming glands are at fault.

    Top of panel Close
  • Shake lotions

    a combination of a powder and liquid that must be shaken before being applied to the skin.

    Top of panel Close
  • Shiatsu

    a Japanese method of massage using gentle finger pressure rather than needles. This Oriental therapy which combines finger pressure on acupuncture points with gentle mobilisation of joints works by enhancing the flow of vital energy through the body.

    Top of panel Close
  • Side effects

    these are adverse events which could happen whilst taking a particular drug and are generally listed following reporting during a trial or after a drug has been in use in the general population as often they are not discovered until that stage.

    Top of panel Close
  • Specialist doctors

    a doctor who specialises in a particular disease such as psoriasis or psoriatic arthritis often based in a hospital.

    Top of panel Close
  • Splint

    an orthopedic device for immobilization, restraint, or support of any part of the body. It may be rigid (of metal, plaster or wood) or flexible (of felt or leather).

    Top of panel Close
  • Spondylitis

    (spon~dil~i~tis) inflammation of vertebrae (spine).

    Top of panel Close
  • Spondylopathy

    any diseased or deformed state of the vertebrae (spine).

    Top of panel Close
  • Stainsby procedure (The)

    is an operation which is used to salvage toes which have developed into a claw deformity. The operation is often for toes which have fused or are in a fixed position and therefore cause pain. The aim is to release the bones by the reposition of the plantar plate under the metatarsal head. Afterwards the toe may look shorter, but pain can be improved.

    Top of panel Close
  • Streptococcal infections

    an infection caused by bacteria. Almost any organ of the body can be involved.

    Top of panel Close
  • Steroid

    an abbreviated word for corticosteroids, which are powerful drugs used to control inflammation and itching of the skin. Very often this is shortened to ‘steroids’ causing people to confuse their skin treatments with the anabolic steroids used for body-building.

    Top of panel Close
  • Stress

    any emotional, physical, social, economic, or other factor that requires a response or change.

    Top of panel Close
  • Stroke

    an area of the brain is deprived of its blood supply - most commonly caused by a blockage (Ischaemic stroke) or burst blood vessel (Haemorrhagic stroke). A transient ischaemic attack (TIA), sometimes called a 'mini-stroke' is when some brain function is temporarily lost because of a short-lived disruption of the blood supply.

    Top of panel Close
  • Stye

    is the inflammation of one of the glands at the edge of the eyelid.

    Top of panel Close
  • Subcutaneous

    beneath the skin.

    Top of panel Close
  • Surgeon

    is a healthcare professional who treats people by cutting or repairing parts of the body.

    Top of panel Close
  • Syndrome

    is a term applied to a group of symptoms occuurring together regularly, such as SAPHO Syndrome.

    Top of panel Close
  • Synovial membrane

    the connective-tissue membrane that lines the cavity of a synovial joint and produces the synovial fluid. Also called synovium.

    Top of panel Close
  • Synovitis

    inflammation of a joint.

    Top of panel Close
  • Synthetic

    pertaining to a substance that is produced by an artificial rather than a natural process or material.

    Top of panel Close
  • Systemic

    referring to the body as a whole.

    Top of panel Close
  • Systemic Lupus Erythematosus (SLE)

    is a progressive and potentially serious disease. It can affect nearly every organ in the body. Among the complications that may be seen are inflammation of the membrane lining the heart and the smooth membranous sac enveloping the heart, pleurisy, kidney lesions and disorders of the central nervous system and skin rash.

    Top of panel Close
  • Systemic therapy

    drugs that affect the whole body.

    Top of panel Close
  • T-cells

    cells that either initiate the immune response (helper T-cells) or actively target and destroy cells perceived as foreign (killer T-cells).

    Top of panel Close
  • T-cell receptors

    molecules on the surface of T-cells that are the sites for macrophages to ‘pre- sent’ antigens to the T-cell and trigger an immune response.

    Top of panel Close
  • Technetium

    a man-made radio-active element used in isotope scans.

    Top of panel Close
  • Telangiectasia

    an increase in the size of blood vessels beneath the skin causing redness and an appearance of broken veins. Most commonly found on the nose and cheeks.

    Top of panel Close
  • T-lymphocytes

    a type of white blood cell within the immune system.

    Top of panel Close
  • Temporal arteritis

    is the inflammation and damage to blood vessels that supply the head area. When the inflammation affects the arteries in the neck, upper body and arms, it is called giant cell arteritis. In approximately 1 in 4 cases the disorder may be present with polymyalgia rheumatica (PMR). Other diseases related with temporal arteritis are systemic lupus erythematosus, rheumatoid arthritis and severe infections.

    Top of panel Close
  • Tendons

    any one of many white, glistening bands of dense fibrous connective tissue that attach muscle to bone.

    Top of panel Close
  • Thrombocytopaenia

    a reduced number of platelets in the blood. This may be a cause of bruising or bleeding and is a potential side-effect from a number of treatments, hence the need for regular blood monitoring.

    Top of panel Close
  • Tietze syndrome

    is an inflammation of the costochondral cartilages of the upper front of the chest. Patients with Tietze syndrome develop tenderness and swelling over the ribs and cartilage near the breast bone Swelling, redness, tenderness, and heat can be present. The pain can vary and is often confused with heart pain, and can last from hours to weeks. It can cause difficulty with sleeping and even rolling over in bed is sometimes painful. Blood testing can show signs of inflammation in patients with Tietze syndrome, whereas blood tests on patients with costochondritis alone typically have normal tests for inflammation.

    Top of panel Close
  • Tissue

    a collection of similar cells acting together to perform a particular function.

    Top of panel Close
  • Topical

    application of medicine is applied to the skin whereas preparations for oral use are taken by mouth.

    Top of panel Close
  • Topical analgesics

    are creams for the treatment of mild to moderate pain caused by arthritis. These are usually only available on prescription.

    Top of panel Close
  • Topical corticosteroids

    suppress the inflammatory reaction during use; they are not curative and on discontinuation a rebound exacerbation of the condition may occur. They are generally used to relieve symptoms and suppress signs of the disorder when other measures such as emollients are ineffective.

    Top of panel Close
  • Toxin

    a poisonous substance, especially one found in the body by germs.

    Top of panel Close
  • Trauma

    Physical injury caused by violent or disruptive action or by the introduction into the body of a toxic substance.

    Physical injury resulting from a severe emotional shock.

    Top of panel Close
  • Trigger

    an environmental factor that acts together with genetic predisposition to cause the onset or worsening of psoriasis.

    Top of panel Close
  • Tumour necrosis factor (TNF)

    a protein in the body involved in inflammatory processes that also damages tissue in and around the joints of people with psoriatic arthritis.

    Top of panel Close
  • UK Dermatology Clinical Trials Network (UK DCTN)

    was formed in February 2002 with the aim of conducting high quality, multi-centre clinical trials that answer questions of importance to clinicians and patients. It involves a collaborative network of dermatologists, dermatology nurses, health services researchers and patients throughout the UK and Southern Ireland.

    Top of panel Close
  • Ultrasound

    this is used both in diagnosis and treatment. High resolution ultrasound equipment has an increasing role in the diagnosis of rheumatic disorders and its value as a treatment tends currently to be underestimated in the UK.

    Top of panel Close
  • Ultraviolet light (UV)

    the part of light that can be used to treat psoriasis but can also cause sunburn.

    • UV-A - Ultraviolet light with wavelengths ranging from 320 to 400 nm
    • UV-B - Ultraviolet light with wavelengths ranging from 290 to 320 nm
    Top of panel Close
  • Vasculitis

    inflammation of blood vessels, a feature of some rheumatic diseases but not psoriatic arthritis

    Top of panel Close
  • Virus

    is a microscopic particle that can infect the cells of a biological organism. Viruses can replicate themselves only by infecting a host cell. They therefore cannot reproduce on their own.

    Top of panel Close
  • Vitamin D analogues

    should not be confused with vitamin tablets or liquids that you may take as dietary supplements. Whilst their chemical structure may be based on a vitamin D3 molecule they have been modified to have a completely different effect.

    Top of panel Close
  • Vitiligo

    light coloured blotches which appear on the skin or hair as a result of the absence of the pigment melanin, the presence of which gives the skin its colour.

    Top of panel Close
  • Vulgaris

    is latin for common and used for the most widespread plaque version, called psoriasis vulgaris.

    Top of panel Close
  • Warts

    common highly contagious but harmless growths on the skin as a result of a virus infection.

    Top of panel Close
  • Wax and wane

    to come and go, often how psoriasis patients describe an acute flare or relapse.

    Top of panel Close
  • White blood cell

    are the cells of the immune system that defend the body against infectious diseases.

    Top of panel Close
  • X Rays

    discovered in 1896 by Professor Röntgen. The main disadvantage of x-ray is the radiation risk. Other techniques of imaging employed are ultrasound or MRI scans, but x-rays are considered useful in specific situations.

    Top of panel Close
  • Yellowish patch

    or onycholysis – this is where the nail becomes detached from the underlying nail bed and a gap develops under the nail.When it starts there is a white or yellowish patch at the tip of the nail, and this then extends down to the cuticle.

    Top of panel Close
  • Yoga

    is a holistic system for promoting homoeostasis at physical, mental and emotional levels. When this balance is disturbed by illness, or the stress created by illness, yoga can help restore it, and help cure or manage the illness.

    Top of panel Close
  • Zygoma

    is the name given to the cheek bone.

    Top of panel Close